The ReMemBrIn Trial: Rehabilitation of Memory following Traumatic Brain Injury

The ReMemBrIn trial is a scientific study investigating the effectiveness of memory rehabilitation for civilians and military personnel with memory problems following traumatic brain injury. The study is coordinated by Dr Roshan das Nair (Nottingham University Hospitals NHS Trust) and Prof Nadina Lincoln (University of Nottingham). 

We will be looking to see how much the rehabilitation programme helps people with memory problems following traumatic brain injury and hopefully improve treatment for these individuals in the future.

What is Traumatic Brain Injury (TBI)?

Traumatic brain injury is an injury to the brain caused by trauma to the head. There are many causes of TBI, such as road traffic accidents, assaults, falls and accidents. There can be many lasting effects of brain injury which are affected by factors such as the location and severity of the brain injury. Often, lasting effects of brain injury can be more extensive than physical injuries and can often be “invisible”, such as memory problems.

Why is memory rehabilitation important?

Memory impairments are one of the most common cognitive deficits (that is, thinking problems) following traumatic brain injury, affecting 40-60% of patients. These types of problems can be extremely debilitating. Some patients may not be able to return to work and their memory problems may negatively affect their social life or relationships.  At the moment, people who have had a brain injury do not always receive any further therapy after they leave hospital to help with their memory problems.

What is the ReMemBrIn trial about?

The aim of the study is to compare a group-based memory rehabilitation programme with usual clinical care.

Where is the trial taking place?

The ReMemBrIn trial is taking place at four centres across the UK: Nottingham, Epsom, Chester and Birmingham. We will also be recruiting participants from sites near to these centres . We are aiming to recruit 400 participants. Adults who have suffered a brain injury are invited to take part.

If you would like further information, please contact our trial team 0115-8844930 or


Newsletter #1 Feb 2013
Newsletter #2 Aug 2013
Newsletter #3 Dec 2013

The ReMemBrIn trial is coordinated by the Nottingham Clinical Trials Unit.

The ReMemBrIn trial is being funded by the National Institute for Health Research Health Technology Assessment (NIHR HTA) Programme (project number 10/57/24) and will be published in full in Health Technology Assessment.

The views and opinions expressed herein are those of the authors and do not necessarily reflect those of the HTA programme, NIHR, NHS or the Department of Health.